β-amyloids

5 posts

Spectroelectrochemical studies of TDMQ20: A potential drug against Alzheimer’s disease

Collaboration is extremely important to us. Gaining new knowledge, both practical and theoretical, is also extremely important. For this reason, Magda went on a 6-month internship to Professor Alvaro Colina’s group in Burgos, Spain. The cooperation turned out to be very successful because shortly after her return our first article […]

Redox behaviour of Cu-Aβ(4-16) complexes related to Alzheimer’s Disease

The next paper in Magda’s series of articles on the redox behaviour of β-amyloids relevant for Alzheimer’s disease has just hit the press. Here we have been looking at how the presence of a redox-active amino acid, tyrosine (Tyr), affects the oxidation of a Cu(II) attached to the amino terminus […]

Very small changes in the peptide sequence alter the redox properties of Aβ(11-16)-Cu(II) and pAβ(11-16)-Cu(II) β-amyloid complexes

Sometimes publishing doesn’t go according to plan…. Our newly published article in J. Electroanal. Chem. was supposed to have been published before the follow-up in ChemElectroChem. We thought it made sense to first study the shorter amyloid and then follow with a study of the longer one. Some review delays […]

The Influence of Coordination Mode on the Redox Properties of Copper Complexes with Aβ(3-16) and its Pyroglutamate Counterpart pAβ(3-16)

Over the last year, Magda has been working with bachelor student Natalia to investigate the redox behaviour of different β-amyloids. In her recently published paper she demonstrates a significant difference in the redox behaviour of copper complexes with peptides associated with Alzheimer’s disease (AD). AD is a neurodegenerative disorder and […]