Polish title: Spektroelektrochemia choroby Alzheimera – badania nowej potencjalnej cząsteczki leczniczej
Funding source: Polish National Science Centre (NCN)
Project number: 2021/40/C/ST4/00090
PI: Magdalena Zofia Wiloch
Total funding: 731 366 PLN
Short description
The project concerns research focused on a TDMQ20 molecule which is one of the most promising molecules against Alzheimer’s disease. How does TDMQ work? The hypothesized working mechanism of TDMQ is based on a Cu(II) ion exchange with Cu(II)-Aβ complexes (where Aβ is a different β‑amyloid peptide), a process which also inhibits the formation of reactive oxygen species – ROS. In this project we are going to check electrochemical as well as spectroelectrochemical behavior changes of different Cu(II)-Aβ complexes after adding TDMQ. The research may be a critical step in verifying the efficacy of TDMQ as an active substance of potential clinical importance, whilst also contributing in general to knowledge about the pathology of Alzheimer’s disease
Post tagged with Sonatina-5